As you may already know if you follow our site closely, a huge update for The Binding of Isaac is planned to release sometime this year titled The Wrath of the Lamb which plans to roughly double the content in the game. Danny B has recently announced that he will in fact be redoing the already delightful soundtrack to the game for the new expansion, itself also receiving roughly as much new content as the original.
This is wonderful news to many players, myself included. The Binding of Isaac is one of very few games that I absolutely can not play without the sound on. Not for a tactical reason like some people with FPS games, but merely for the enjoyment I get each time out of hearing the wonderful music.