Bioware is Aware of Mass Effect 2 PS3 Save Issues
Players of Mass Effect 2 for the PS3 have been reporting issues of their save-games getting erased, or in reported cases their entire HDD getting reformated. Bioware has spoken up that they’ve taken note and are aware of these issues, and are working on a fix for the problem ASAP. If you’ve encountered the issue they’d like for you to contact them with details on your PS3 and your playthrough. It sounds like they’re still trying to figure out what’s causing the issue.