Nintendo Treehouse has shown some footage of Mario Party 10. In the demo there was a playable mode called “Bowser Party”. In that game mode, Bowser has the ability to throw multiple dice blocks to be able to catch up to Mario and his friends. Each player has six hearts and if Bowser can get rid of them all then he wins.
When Bowser catches up to Mario and the gang a special Bowser mini game will initiate.