Warframe players have been waiting for the latest Nidus Prime Plague Star update ever since it was teased at the Tennocon event.

With this update, the popular Operation Plague Star event is back and you can click on the link to know more details like how to start and complete the event.

An important part of the Plague Star event is collecting the Hemocyte Cystolith. If you haven't played this event before then we have all the information you need to know about this special drop.

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What Is Hemocyte Cystolith In Warframe?

Hemocyte Cystolith Warframe

Hemocyte Cystolith is a resource dropped by the Hemocyte during Operation: Plague Star. It is used to build that event's clan trophies.

Please note that Cystoliths cannot be traded between players, and cannot be sold for credits either.

How To Get It

You can get a Hemocyte Cystolith by killing a Hemocyte in Warframe.

The latest patch notes for Warframe mention certain changes to the Hemocyte which you should know before you go hunting for them. First of all, Hemocyte has been made immune to looting abilities. Besides that, Nidus Prime’s Relics appear as drops from the Hemocyte. You can check out the new details below:

  • Hemocyte is now immune to looting abilities that often didn’t fully work due to how quickly the body despawns (Hydroid’s Tentacle Swarm with Pilfering Swarm, Nekros’ Desecrate etc).
    • With the re-run of Plague Star, we are adding Nidus Prime’s Relics as in-world drops from the Hemocyte. This change was brought forth with this in mind, and the acquisition rate of this new Prime that could be influenced with loot abilities which is not a precedent we wish to set. With up to 4 Hemocytes that can spawn in the final stage it felt especially important to make this change.

How To Use Hemocyte Cystolith

The sole purpose of Hemocyte Cystolith is to act as a resource for building the Clan Trophy from the event. So if you are in a Clan, don't forget to pick them up each time after killing a Hemocyte, because this will help your Clan to build the trophies.

To build a Clan trophy, here's the number of Hemocyte Cystolith (HC) you will need:

  • Terracotta – 10 HC
  • Bronze – 25 HC
  • Silver – 50 HC
  • Gold – 100 HC

Depending on your Clan size, a multiplier can also be applied as mentioned below:

  • Ghost Clan x 1
  • Shadow Clan x 3
  • Storm Clan x 10
  • Mountain Clan x 30
  • Moon Clan x 100

So this was everything you needed to know about Hemocyte Cystolith in Warframe. For more details, you can refer to this page.